MovDisordV3, Main, Exploration, bibRecord, 001F58

Depression and the Subsequent Risk of Parkinson's Disease in the NIH-AARP Diet and Health Study

Identifieur interne : 001F58 ( Main/Exploration ); précédent : 001F57; suivant : 001F59

Depression and the Subsequent Risk of Parkinson's Disease in the NIH-AARP Diet and Health Study

Auteurs : FANG FANG [États-Unis, Suède] ; QUN XU [États-Unis] ; YIKYUNG PARK [États-Unis] ; XUEMEI HUANG [États-Unis] ; Albert Hollenbeck [États-Unis] ; Aaron Blair [États-Unis] ; Arthur Schatzkin [États-Unis] ; Freya Kamel [États-Unis] ; HONGLEI CHEN [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2010.

RBID : Pascal:10-0376007

Descripteurs français

Pascal (Inist)
- Etat dépressif, Maladie de Parkinson, Pathologie du système nerveux, Facteur risque.

English descriptors

KwdEn :
- Depression, Nervous system diseases, Parkinson disease, Risk factor.

Abstract

We conducted a case-control study to examine the association between depression and Parkinson's disease (PD). Participants included 992 PD cases diagnosed after 2,000 and 279,958 individuals without PD from the NIH-AARP Diet and Health Study follow-up survey. Physician-diagnosed depression and PD were self-reported with information on the year of diagnosis in the following categories: before 1985, 1985-1994, 1995-1999, and 2000-present. Only PD cases diagnosed after 2000 were included in the analysis. Odds ratios (ORs) and 95% confidence intervals (CIs) were derived from logistic regression models, adjusted for age, gender, educational level, marital status, smoking, and coffee drinking. Individuals with depression diagnosed after 2000 were more likely to report a concurrent diagnosis of PD than those without depression (OR = 4.7, 95% CI = 3.9, 5.7). Depression diagnosed before 2000 was also associated with higher odds of PD diagnosed after 2000 (OR = 2.0, 95% CI = 1.6, 2.4). This association was stronger for depression diagnosed in 1995-1999 (OR = 2.7, 95% CI = 2.0, 3.6), but was also noted for depression diagnosed in 1985-1994 (OR = 1.6, 95% CI = 1.1, 2.3) or even before 1985 (OR = 1.7, 95% CI = 1.3, 2.3). This association was not modified by other factors and persisted in an analysis excluding participants who reported poor health status. The results suggest that depression may either be a very early symptom of PD or share common etiological factors with PD.

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">We conducted a case-control study to examine the association between depression and Parkinson's disease (PD). Participants included 992 PD cases diagnosed after 2,000 and 279,958 individuals without PD from the NIH-AARP Diet and Health Study follow-up survey. Physician-diagnosed depression and PD were self-reported with information on the year of diagnosis in the following categories: before 1985, 1985-1994, 1995-1999, and 2000-present. Only PD cases diagnosed after 2000 were included in the analysis. Odds ratios (ORs) and 95% confidence intervals (CIs) were derived from logistic regression models, adjusted for age, gender, educational level, marital status, smoking, and coffee drinking. Individuals with depression diagnosed after 2000 were more likely to report a concurrent diagnosis of PD than those without depression (OR = 4.7, 95% CI = 3.9, 5.7). Depression diagnosed before 2000 was also associated with higher odds of PD diagnosed after 2000 (OR = 2.0, 95% CI = 1.6, 2.4). This association was stronger for depression diagnosed in 1995-1999 (OR = 2.7, 95% CI = 2.0, 3.6), but was also noted for depression diagnosed in 1985-1994 (OR = 1.6, 95% CI = 1.1, 2.3) or even before 1985 (OR = 1.7, 95% CI = 1.3, 2.3). This association was not modified by other factors and persisted in an analysis excluding participants who reported poor health status. The results suggest that depression may either be a very early symptom of PD or share common etiological factors with PD.</div>
</front>
</TEI>
<affiliations><list><country><li>Suède</li>
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<tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Fang Fang" sort="Fang Fang" uniqKey="Fang Fang" last="Fang Fang">FANG FANG</name>
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<name sortKey="Qun Xu" sort="Qun Xu" uniqKey="Qun Xu" last="Qun Xu">QUN XU</name>
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<name sortKey="Xuemei Huang" sort="Xuemei Huang" uniqKey="Xuemei Huang" last="Xuemei Huang">XUEMEI HUANG</name>
<name sortKey="Yikyung Park" sort="Yikyung Park" uniqKey="Yikyung Park" last="Yikyung Park">YIKYUNG PARK</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Depression and the Subsequent Risk of Parkinson's Disease in the NIH-AARP Diet and Health Study

Depression and the Subsequent Risk of Parkinson's Disease in the NIH-AARP Diet and Health Study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri